2017-12-07 13:14:172025-05-24 03:13:36

description

DNA polymerase III, leading strand polymerase (alpha subunit), part of the replisome

DNA polymerase III, leading strand polymerase (alpha subunit), part of the [SW|replisome]

locus

BSU16580

BSU_16580

function

DNA replication

[[category|DNA replication]]

outlinks

bsu

BSU16580

BSU_16580

The protein

Catalyzed reaction/ biological activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1) (according to Swiss-Prot)

required for bacteriophage SPP1 replication [Pubmed|23268446]

2'-deoxyribonucleoside 5'-triphosphate + DNA_(n) --> diphosphate + DNA_(n+1) (according to UniProt)

required for bacteriophage SPP1 replication [Pubmed|23268446]

The protein

Protein family

PolC subfamily (according to Swiss-Prot)

DNA polymerase type-C family (with [[protein|YorL]] and [[protein|DnaE]], according to UniProt)

References

Reviews

19106294, 28073967

19106294, 28073967, 29197672

References

Original publications

15186423, 20122408, 11721055, 23563155, 23268446, 21740522, 21958350, 24062730, 24106089, 19106298, 28002733, 28575448, 28878042

15186423, 20122408, 11721055, 23563155, 23268446, 21740522, 21958350, 24062730, 24106089, 19106298, 28002733, 28575448, 28878042, 30686488, 31251806

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Domains]

[SW|Exonuclease domain] (aa 421-578) (according to UniProt)